PROFIL PRACOWNIKA: Michał Ponczek
SCIENTIFIC AND SOCIAL MEDIA PROFILES
POSITION DESCRIPTION
Position: Research and teaching assistant professor. The scope of duties includes: didactic activity at first-, second- and third-cycle studies, conducting scientific research and sharing results and discoveries with the scientific community and the society in the form of prepared publications, as well as organizational activities.
https://www.researchgate.net/lab/Michal-Blazej-Pon...
Supervision of PhD student:
BIOGRAPHICAL NOTE
STUDIES
biochemistry
Year of Completion:
2003
DEGREES AND TITLES
Habilitation
Domain:
Biological Sciences
Discipline:
biochemistry
Specialties:
bioinformatics, bioinformatics
Date of Degree:
26/09/2017
Thesis title:
Institution:
University of Lodz; Faculty of Biology and Environmental Protection
Doctorate
Domain:
Biological Sciences
Discipline:
biochemistry
Specialty:
Biochemistry of blood coagulation
Date of Degree:
23/10/2007
Thesis title:
Changes in fibrinogen coagulation activity due to reactive nitrogen and oxygen species
26 SEP 2017 Assistant professor with habilitation at the University of Lodz, Department of General Biochemistry. habilitation thesis "Application of bioinformatics and computational chemistry in the study of evolution and biochemical processes of serine proteases of blood coagulation and fibrinolysis".
1 OCT 2008 Assistant professor at the University of Lodz, Department of General Biochemistry.
11 APR - 11 JUL 2008 EMBO Short-Term Fellowship (ASTF 83.00-2008) at the University of California, San Diego.
1 DEC 2007 Research associate at the University of Lodz, Department of General Biochemistry.
23 OCT 2007 PH.D degree in biochemistry - doctorate thesis: "Changes of fibrinogen coagulation properties induced by reactive nitrogen and oxygen species" .
INTERESTS
The ultimate question of life the universe and everything?
Scientific research interests:
Structural biology of proteins of hemostatic proteins CryoEM, and above all the contact system and kininogenesis system using the technique of cryoelectron microscopy(CryoEM) - studying the structure of kininogens. Docking ligands in the search for new drugs and learning about protein functions. Molecular evolution, phylogenetics, molecular modelling, docking, dynamics and bioinformatics in the field of biochemistry of proteins of hemostasis and drug design, with particular emphasis on the importance of contact proteases (FXI, FXII, PK) in thrombotic diseases. Simulations of ligand binding to proteins - molecular docking. Structural prediction, modelling, molecular dynamics and other analyses of proteins. Drug likeliness prediction. Molecular mechanisms of modifications caused by oxidative stress in proteins of blood coagulation system.
ACHIEVEMENTS
Recent publications:
High Molecular Weight Kininogen: A Review of the Structural Literature by Michał B. Ponczek. Int. J. Mol. Sci. 2021, 22(24), 13370; https://doi.org/10.3390/ijms222413370
Received: 29 October 2021 / Reviewed: 2 December 2021 / Accepted: 11 December 2021 / Published: 13 December 2021
https://www.mdpi.com/1422-0067/22/24/13370?fbclid=...
Finding inhibitors for PCSK9 using computational methods. Rida Zainab, Afshan Kaleem ,Michael B. Ponczek ,Roheena Abdullah,Mehwish Iqtedar,Daniel C. Hoessli. Published: August 5, 2021 https://doi.org/10.1371/journal.pone.0255523
https://journals.plos.org/plosone/article?id=10.13...
Scientific visits abroad
- Visiting Scholar, June 2019 - July 2019, Department of Pathology, Microbiology and Immunology, Nashville, USA
- Postdoctoral Fellow, EMBO Short-Term Fellowship ASTF 83.00-2008, April 2008 - June 2008, Department of Chemistry and Biochemistry, San Diego, USA